Selected Publications

Machine Learning Algorithms

  • Valdes G, Friedman J, Jiang F, Gennatas E. Representational Gradient Boosting: Backpropagation in the Space of Functions. IEEE Trans Pattern Anal Mach Intell. 2021

  • Valdes G, Interian Y, Gennatas E, Van der Laan M. The Conditional Super Learner. IEEE Trans Pattern Anal Mach Intell. 2021

  • Gennatas ED, Friedman JH, Ungar LH, Pirracchio R, Eaton E, Reichman L, Interian Y, Simone CB, Auerbach A, Delgado E, Van der Laan MJ, Solberg TD, Valdes G. Expert-Augmented Machine Learning. Proc Natl Acad Sci USA 2020

  • Luna JM*, Gennatas ED*, Eaton E, Diffenderfer E, Ungar LH, Jensen ST, Charles SB II, Friedman JH, Solberg TD, Valdes G. Building more accurate decision trees with the Additive Tree. Proc Natl Acad Sci USA 2019 *Equal contribution

Computer Science Conference Papers

  • Gennatas ED, Interian Y, Solberg TD, Van der Laan MJ, Valdes G. Conditionally Interpretable SuperLearner. Neural Information Processing Systems 2018

  • Luna JM, Eaton E, Ungar LH, Diffenderfer E, Jensen ST, Gennatas ED, Wirth M, Charles SB, Solberg TD, Valdes G Tree-Structured Boosting: Connections Between Gradient Boosted Stumps and Full Decision Trees arXiv:1711.06793. Neural Information Processing Systems 2017 Symposium on Interpretable Machine Learning

Neuroscience, Neurology, Psychiatry

  • Gennatas ED, Wren-Jarvis J, Powers R, Lazerwitch MC, Bourla I, Cai LT, Choi HL, Chu R, Trimarchi KJ, Garcia RD, Marco EJ, Mukherjee P. Gray Matter Correlates of Attention Deficit Hyperactivity Disorder in Boys versus Girls with Sensory Processing Dysfunction. Imaging Neuroscience 2024

  • Gur RC, Butler ER, Moore TM, Rosen AF, Ruparel K, Satterthwaite TD, Roalf DR, Gennatas ED, Bilker WB, Shinohara RT, Port A, Elliott MA, Verma R, Davatzikos C, Wolf DH, Deter JA, Gur RE. Structural and Functional Brain Parameters Related to Cognitive Performance Across Development: Replication and Extension of the Parieto-Frontal Integration Theory in a Single Sample. Cerebral cortex 2020

  • Butler PM, Chiong W, Perry DC, Miller ZA, Gennatas ED, Brown JA, Pasquini L, Karydas A,Dokuru D, Coppola G, Sturm VE, Boxer AL, Gorno-Tempini ML, Rosen HJ, Kramer JH, Miller BL, Seeley WW, Dopamine receptor D4 (DRD4) polymorphisms with reduced functional potency intensify atrophy in syndrome-specific sites of frontotemporal dementia. NeuroImage: Clinical 2019

  • Rosen AFG, Roalf DR, Ruparel K, Blake J, Seelaus K, Villa LP, Ciric R, Cook PA, Davatzikos C, Elliott MA, Garcia de La Garza A, Gennatas ED, Quarmley M, Schmitt JE, Shinohara RT, Tisdall MD, Craddock RC, Gur RE, Gur RC, Satterthwaite TD. Quantitative assessment of structural image quality. Neuroimage. 2018

  • Vandekar SN, Shou H, Satterthwaite TD, Shinohara RT, Merikangas AK, Roalf DR, Ruparel K, Rosen A, Gennatas ED, Elliott MA, Davatzikos C, Gur RC, Gur RE, Detre JA. Sex differences in estimated brain metabolism in relation to body growth through adolescence. J Cereb Blood Flow Metab. 2017

  • Gennatas ED, Avants BB, Wolf DH, Satterthwaite TD, Ruparel K, Ciric R, Hakonarson H, Gur RE, Gur RC. Age-related effects and sex differences on gray matter density, volume, mass, and cortical thickness from childhood to young adulthood. J Neurosci. 2017 (Featured on the cover and editorial)

  • Aguirre GK, Datta R, Benson NC, Prasad S, Jacobson SG, Cideciyan AV, Bridge H, Watkins KE, Butt OH, Dain AS, Brandes L, Gennatas ED. Patterns of Individual Variation in Visual Pathway Structure and Function in the Sighted and Blind. Ptito M, ed. PLoS ONE. 2016

  • Kaczkurkin AN, Moore TM, Ruparel K, Ciric R, Calkins ME, Shinohara RT, Elliott MA, Hopson R, Roalf DR, Vandekar SN, Gennatas ED, Wolf DH, Scott JC, Pine DS, Leibenluft E, Detre JA, Foa EB, Gur RE, Gur RC, Satterthwaite TD. Elevated Amygdala Perfusion Mediates Developmental Sex Differences in Trait Anxiety. Biol Psychiatry. 2016

  • Shanmugan S, Wolf DH, Calkins ME, Moore TM, Ruparel K, Hopson RD, Vandekar SN, Roalf DR, Elliott MA, Jackson C, Gennatas ED, Leibenluft E, Pine DS, Shinohara RT, Hakonarson H, Gur RC, Gur RE, Satterthwaite TD. Common and Dissociable Mechanisms of Executive System Dysfunction Across Psychiatric Disorders in Youth. Am J Psychiatry. 2016

  • Guo CC, Sturm VE, Zhou J, Gennatas ED, Trujillo AJ, Hua AY, Crawford R, Stables L, Kramer JH, Rankin K, Levenson RW, Rosen HJ, Miller BL, Seeley WW. Dominant hemisphere lateralization of cortical parasympathetic control as revealed by frontotemporal dementia. Proc Natl Acad Sci USA. 2016

  • Roalf DR, Quarmley M, Elliott MA, Satterthwaite TD, Vandekar SN, Ruparel K, Gennatas ED, Calkins ME, Moore TM, Hopson R, Prabhakaran K, Jackson CT, Verma R, Hakonarson H, Gur RC, Gur RE. The impact of quality assurance assessment on diffusion tensor imaging outcomes in a large-scale population-based cohort. Neuroimage. 2016

  • Satterthwaite TD, Vandekar SN, Wolf DH, Bassett DS, Ruparel K, Shehzad Z, Craddock RC, Shinohara RT, Moore TM, Gennatas ED, Jackson C, Roalf DR, Milham MP, Calkins ME, Hakonarson H, Gur RC, Gur RE. Connectome-wide network analysis of youth with Psychosis-Spectrum symptoms. Mol Psychiatry. 2015

  • Satterthwaite TD, Wolf DH, Roalf DR, Ruparel K, Erus G, Vandekar S, Gennatas ED, Elliott MA, Smith A, Hakonarson H, Verma R, Davatzikos C, Gur RE, Gur RC. Linked Sex Differences in Cognition and Functional Connectivity in Youth. Cerebral Cortex. 2015

  • Satterthwaite TD, Shinohara RT, Wolf DH, Hopson RD, Elliott MA, Vandekar SN, Ruparel K, Calkins ME, Roalf DR, Gennatas ED, Jackson C, Erus G, Prabhakaran K, Davatzikos C, Detre JA, Hakonarson H, Gur RC, Gur RE. Impact of puberty on the evolution of cerebral perfusion during adolescence. Proc Natl Acad Sci USA. 2014

  • Satterthwaite TD, Wolf DH, Ruparel K, Erus G, Elliott MA, Eickhoff SB, Gennatas ED, Jackson C, Prabhakaran K, Smith A, Hakonarson H, Verma R, Davatzikos C, Gur RE, Gur RC. Heterogeneous impact of motion on fundamental patterns of developmental changes in functional connectivity during youth. Neuroimage. 2013

  • Satterthwaite TD, Wolf DH, Erus G, Ruparel K, Elliott MA, Gennatas ED, Hopson R, Jackson C, Prabhakaran K, Bilker WB, Calkins ME, Loughead J, Smith A, Roalf DR, Hakonarson H, Verma R, Davatzikos C, Gur RC, Gur RE. Functional maturation of the executive system during adolescence. J Neurosci. 2013

  • Gardner RC, Boxer AL, Trujillo A, Mirsky JB, Guo CC, Gennatas ED, Heuer HW, Fine E, Zhou J, Kramer JH, Miller BL, Seeley WW. Intrinsic connectivity network disruption in progressive supranuclear palsy. Ann Neurol. 2013

  • Gennatas ED, Cholfin JA, Zhou J, Crawford RK, Sasaki DA, Karydas A, Boxer AL, Bonasera SJ, Rankin KP, Gorno-Tempini ML, Rosen HJ, Kramer JH, Weiner M, Miller BL, Seeley WW. COMT Val158Met genotype influences neurodegeneration within dopamine-innervated brain structures. Neurology. 2012

  • Zhou J, Gennatas ED, Kramer JH, Miller BL, Seeley WW. Predicting regional neurodegeneration from the healthy brain functional connectome. Neuron. 2012

  • Rohrer JD, Geser F, Zhou J, Gennatas ED, Sidhu M, Trojanowski JQ, Dearmond SJ, Miller BL, Seeley WW. TDP-43 subtypes are associated with distinct atrophy patterns in frontotemporal dementia. Neurology. 2010

  • Zielinski BA, Gennatas ED, Zhou J, Seeley WW. Network-level structural covariance in the developing brain. Proc Natl Acad Sci USA. 2010

  • Zhou J, Greicius MD, Gennatas ED, Growdon ME, Jang JY, Rabinovici GD, Kramer JH, Weiner M, Miller BL, Seeley WW. Divergent network connectivity changes in behavioural variant frontotemporal dementia and Alzheimer’s disease. Brain. 2010

Radiation Oncology

  • Valdes G, Scholey J, Nano T, Gennatas ED, Mohindra P, Mohammed N, Zeng J, Kotesha RD, Rosen LR, Chang J, Tsai HK, Urbanic JJ, Vargas CE, Nathan YY, Ungar LH, Eaton E, Simone II CB. Predicting the Effect of Proton Beam Therapy Technology on Pulmonary Toxicities for Patients With Locally Advanced Lung Cancer Enrolled in the Proton Collaborative Group Prospective Clinical Trial. International Journal of Radiation Oncology* Biology* Physics 2023

  • Morin O, Chen W, Gennatas E, Magill S, Wu A, Valdes G, Perry A, Sneed P, McDermott M, Solberg T, Oberheim Bush NA, Braunstein S, Villanueva-Meyer J, Raleigh D. Preoperative quantitative imaging features are prognostic for meningioma outcomes. Neuro-Oncology, Volume 20, Issue suppl_6, 5 November 2018

  • Gennatas ED, Wu A, Braunstein SE, Morin O, Chen WC, Magill ST, Gopinath C, Villaneueva-Meyer JE, Perry A, McDermott MW, Solberg TD. Preoperative and postoperative prediction of long-term meningioma outcomes. PloS ONE. 2018 Sep 20;13(9):e0204161. (Featured in Machine Learning in Health and Biomedicine special issue)

  • Interian Y, Rideout V, Kearney VP, Gennatas E, Morin O, Cheung J, Solberg T, Valdes G. Deep nets vs expert designed features in medical physics: An IMRT QA case study. Med Phys. 2018

Preprints - not otherwise published

  • Valdes G, Interian Y, Gennatas ED, van der Laan MJ. Condition Super Learner. arXiv:1912.06675, 2019

  • Gur RC, Moore TM, Rosen AFG, Ruparel K, Satterthwaite TD, Roalf DR, Gennatas ED, Bilker WB, Shinohara RT, Port A, Elliott MA, Verma R, Davatzikos C, Wolf DH, Detre JA, Gur RE. Multimodal parameters of brain structure and function related to sex differences in cognitive performance. bioRxiv 2019; 659193.

  • Luna JM, Eaton E, Ungar LH, Diffenderfer E, Jensen ST, Gennatas ED, Wirth M, Charles SB, Solberg TD, Valdes G Tree-Structured Boosting: Connections Between Gradient Boosted Stumps and Full Decision Trees arXiv:1711.06793 2017